PROJECTS
Congenital Muscular Distrophy associated to LMNA
Aims of the project
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Generation of disease models for the study of underlying mechanisms and testing new therapeutic strategies
Potential of CRISPR/Cas9 based gene therapies both in cells and in vivo
Validation of pharmacological candidates
Rare Cancers: mechanisms and therapies
Aims of the project
Modeling: cell lines, canceroids and animal models.
Study of the potential of CRISPR/Cas9 mediated gene editing.
New, and personalized, therapeutic strategies.
Chromosome instability and Cancer
Aims of the project
Search of CIN associated cancer biomarkers.
Analysis of TPX2 non-mitotic functions.
Role of Aurora A kinase in cancer development and progression.
New anti-tumoral therapies associated with CIN.
Collaborators
Dr. Jesús García-Donás
Susana H Boj
Sergio Casas
Dra. Maria Jesus Vicent
Dr. Juanfer García
Dra. Gema Moreno
Dr. Ángel Martínez
Dr. Lluis Montoliu
Dra. Beatriz Martínez-Delgado
Dra. Pilar Sánchez
Dr. Marcos Malumbres
Dra. Mercedes Robledo
Dr. Gonzalo Gómez
Dra. Francisca Vicente
Dr. Bastien Cautain
Dra. Meritxell Huch